Qualitative and quantitative analysis of cardiac 4D PC-MRI blood flow data

Partners: Heart Center in Leipzig (Matthias Gutberlet, Matthias Grothoff)

The genesis and progression of cardiovascular diseases (CVDs) depend on various factors. A better comprehension of patient-specific blood flow hemodynamics has great potential to increase their diagnosis, support treatment decision-making and provide a realistic forecast of such pathologies, facilitating a better implementation of preventative measures. Four-dimensional phase-contrast magnetic resonance imaging (4D PC-MRI) gained increasing importance and clinical attention in recent years. It is a non-invasive imaging modality that allows for time-resolved, three-dimensional measurement of blood flow information. The resulting 4D grid data, which contain vectors that represent the blood flow direction and velocity, are of limited spatio-temporal resolution and suffer from multiple artifacts, making complex image processing methods a prerequisite. Qualitative data analysis aims to depict the course of the blood flow with emphasis on specific flow patterns, such as vortex flow, which can be an indicator for different cardiovascular diseases. For this purpose, flow visualization techniques can be adapted to the cardiac context. Quantitative data analysis facilitates assessment of, e.g., the cardiac function by evaluating stroke volumes, heart valve performances by evaluating percentaged back flows, and fluid-vessel wall interactions by evaluating wall shear stress.

In this project both qualitative and quantitative data evaluation methods are developed, embedded in a developed software prototype with a guided workflow.

A semi-automatic extraction of vortex flow was established that is based on the line predicates methodology and preserves visually appealing path lines with long and continuous courses. It was tailored towards our targeted user group: Radiologists focused on the cardiovascular system and cardiologists. The extracted path lines were used to establish an overview visualization of aortic vortex flow and to adapt the speed of videos so that the display vortical flow behavior is enhanced. Vortices were grouped into single entities (clustering) and subsequently analyzed according to different criteria that describe properties, such as their rotation direction and elongation. Based on this classification, a simplifying glyph visualization was established.
Moreover, the improved quantification of flow rate-based measures was addressed, such as stroke volumes, which are prone to errors especially in case of pathologic vortex flow. A robust procedure was developed that analyzes multiple, systematically generated configurations of required measuring planes and evaluates the resulting sample distributions. Additionally, the flow rate calculation is influenced by the dynamic morphology. Therefore, a semi-automatic extraction of corresponding motion information was established and incorporated in an adapted quantification.

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Publications

2020
	Sebastian Ebel, Josefin Dufke, Benjamin Köhler, Bernhard Preim, Benjamin Behrendt, Boris Riekena, Bernd Jung, Christian Stehning, Siegfried Kropf, Matthias Grothoff, Matthias Gutberlet Automated quantitative extraction and analysis of 4D flow patterns in the ascending aorta -- an intraindividual comparison at 1.5 T and 3 T Journal Article Scientific reports, 10.2020 , pp. 9 Seiten, 2020. BibTeX @article{Ebel_2020, title = {Automated quantitative extraction and analysis of 4D flow patterns in the ascending aorta -- an intraindividual comparison at 1.5 T and 3 T}, author = {Sebastian Ebel and Josefin Dufke and Benjamin Köhler and Bernhard Preim and Benjamin Behrendt and Boris Riekena and Bernd Jung and Christian Stehning and Siegfried Kropf and Matthias Grothoff and Matthias Gutberlet}, year = {2020}, date = {2020-01-01}, journal = {Scientific reports}, volume = {10.2020}, pages = {9 Seiten}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
2019
	Sebastian Ebel, Josefin Dufke, Benjamin Köhler, Bernhard Preim, Susan Rosemeier, Bernd Jung, Michael Borger, Matthias Grothoff, Matthias Gutberlet Comparison of two accelerated 4D-Flow sequences for aortic flow quantification Inproceedings Scientific Reports, 2019. BibTeX @inproceedings{Ebel_2019_ScR, title = {Comparison of two accelerated 4D-Flow sequences for aortic flow quantification}, author = {Sebastian Ebel and Josefin Dufke and Benjamin Köhler and Bernhard Preim and Susan Rosemeier and Bernd Jung and Michael Borger and Matthias Grothoff and Matthias Gutberlet}, year = {2019}, date = {2019-01-01}, booktitle = {Scientific Reports}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Sebastian Ebel, Lisa Hübner, Benjamin Köhler, Siegfried Kropf, Bernhard Preim, Bernd Jung, Matthias Grothoff, Matthias Gutberlet Validation of two accelerated 4D flow MRI sequences at 3T: a phantom study Inproceedings European Radiology Experimental, pp. 1–12, Springer International Publishing, 2019. BibTeX \| Links: @inproceedings{Ebel_ERE_2019, title = {Validation of two accelerated 4D flow MRI sequences at 3T: a phantom study}, author = {Sebastian Ebel and Lisa Hübner and Benjamin Köhler and Siegfried Kropf and Bernhard Preim and Bernd Jung and Matthias Grothoff and Matthias Gutberlet}, url = {https://www.vismd.de/wp-content/uploads/legacy/ebel_ere_2019.pdf, PDF Download}, doi = {https://doi.org/10.1186/s41747-019-0089-2}, year = {2019}, date = {2019-01-01}, booktitle = {European Radiology Experimental}, volume = {3}, number = {1}, pages = {1--12}, publisher = {Springer International Publishing}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Bloodline: A system for the guided analysis of cardiac 4D PC-MRI data Journal Article Computers & Graphics, 82 , pp. 32–43, 2019. BibTeX \| Links: @article{Koehlerd, title = {Bloodline: A system for the guided analysis of cardiac 4D PC-MRI data}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.youtube.com/watch?v=Iyo-ge12qhI, YouTube}, doi = {10.1016/j.cag.2019.05.004}, year = {2019}, date = {2019-01-01}, journal = {Computers & Graphics}, volume = {82}, pages = {32--43}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
2018
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Visual and Quantitative Analysis of Great Arteries' Blood Flow Jets in Cardiac 4D PC-MRI Data Journal Article Computer Graphics Forum, 37 (3), pp. 195-204, 2018. BibTeX \| Links: @article{Koehler_2018_CGF, title = {Visual and Quantitative Analysis of Great Arteries' Blood Flow Jets in Cardiac 4D PC-MRI Data}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2018_cgf.pdf, PDF Download https://www.youtube.com/watch?v=WL7aw2XeAhY, YouTube}, doi = {10.1111/cgf.13412}, year = {2018}, date = {2018-01-01}, journal = {Computer Graphics Forum}, volume = {37}, number = {3}, pages = {195-204}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Pressure-based vortex extraction in cardiac 4D PC-MRI blood flow data Inproceedings EuroVis 2018: Eurographics / IEEE VGTC Conference on Visualization 2018, pp. to appear, 2018. BibTeX \| Links: @inproceedings{Koehler_2018_EuroVIS, title = {Pressure-based vortex extraction in cardiac 4D PC-MRI blood flow data}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2018_eurovis.pdf, PDF Download}, year = {2018}, date = {2018-01-01}, booktitle = {EuroVis 2018: Eurographics / IEEE VGTC Conference on Visualization 2018}, pages = {to appear}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Mickaël Francisco Sereno, Benjamin Köhler, Bernhard Preim Comparison of Divergence-Free Filters for Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 139–144, Springer Verlag, Erlangen, 2018. BibTeX \| Links: @inproceedings{Sereno_2018_BVM, title = {Comparison of Divergence-Free Filters for Cardiac 4D PC-MRI Data}, author = {Mickaël Francisco Sereno and Benjamin Köhler and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/sereno_2018_bvm.pdf, PDF Download}, year = {2018}, date = {2018-00-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {139--144}, publisher = {Springer Verlag}, address = {Erlangen}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2017
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Visualization of Cardiac Blood Flow Using Anisotropic Ambient Occlusion for Lines Inproceedings Vision, Modelling und Visualization (VMV), Bonn, 2017. BibTeX \| Links: @inproceedings{Koehler_2017_VMV, title = {Visualization of Cardiac Blood Flow Using Anisotropic Ambient Occlusion for Lines}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2017_vmv.pdf, PDF Download https://www.youtube.com/watch?v=Y2_SFCFm6Hg, YouTube}, year = {2017}, date = {2017-00-01}, booktitle = {Vision, Modelling und Visualization (VMV)}, address = {Bonn}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2016
	Benjamin Behrendt, Benjamin Köhler, Daniel Gräfe, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Semi-Automatic Vessel Boundary Detection in Cardiac 4D PC-MRI Data Using FTLE fields Inproceedings Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM), pp. 41–46, Bergen, Norwegen, 2016. BibTeX \| Links: @inproceedings{Behrendt_2016_VCBM, title = {Semi-Automatic Vessel Boundary Detection in Cardiac 4D PC-MRI Data Using FTLE fields}, author = {Benjamin Behrendt and Benjamin Köhler and Daniel Gräfe and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/behrendt_2016_vcbm.pdf, PDF Download}, year = {2016}, date = {2016-09-01}, booktitle = {Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM)}, pages = {41--46}, address = {Bergen, Norwegen}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Behrendt, Benjamin Köhler, Uta Preim, Bernhard Preim Enhancing Visibility of Blood Flow in Volume Rendered Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 188–193, Berlin, 2016. BibTeX \| Links: @inproceedings{Behrendt_2016_BVM, title = {Enhancing Visibility of Blood Flow in Volume Rendered Cardiac 4D PC-MRI Data}, author = {Benjamin Behrendt and Benjamin Köhler and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/behrendt_2016_bvm.pdf, PDF Download https://www.youtube.com/watch?v=G0t9_2xSB28, YouTube}, year = {2016}, date = {2016-01-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {188--193}, address = {Berlin}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Silvia Born, Roy Van Pelt, Anja Hennemuth, Uta Preim, Bernhard Preim A Survey of Cardiac 4D PC-MRI Data Processing Journal Article Computer Graphics Forum, 2016. BibTeX \| Links: @article{Koehler_2016_CGF, title = {A Survey of Cardiac 4D PC-MRI Data Processing}, author = {Benjamin Köhler and Silvia Born and Roy Van Pelt and Anja Hennemuth and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2016_cgf.pdf, PDF Download}, year = {2016}, date = {2016-01-01}, journal = {Computer Graphics Forum}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Adaptive Animations of Vortex Flow Extracted from Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 194–199, 2016. BibTeX \| Links: @inproceedings{Koehler_2016_BVM, title = {Adaptive Animations of Vortex Flow Extracted from Cardiac 4D PC-MRI Data}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2016_bvm.pdf, PDF Download https://www.youtube.com/watch?v=6k9DTCvYXDs, YouTube}, year = {2016}, date = {2016-01-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {194--199}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Monique Meuschke, Benjamin Köhler, Uta Preim, Bernhard Preim, Kai Lawonn Semi-automatic Vortex Flow Classification in 4D PC-MRI Data of the Aorta Inproceedings EuroVis 2016: Eurographics / IEEE VGTC Conference on Visualization 2016, pp. 351–360, 2016. BibTeX \| Links: @inproceedings{Meuschke_2016_EuroVis, title = {Semi-automatic Vortex Flow Classification in 4D PC-MRI Data of the Aorta}, author = {Monique Meuschke and Benjamin Köhler and Uta Preim and Bernhard Preim and Kai Lawonn}, url = {https://www.vismd.de/wp-content/uploads/legacy/meuschke_2016_eurovis.pdf, PDF Download https://www.youtube.com/watch?v=steqJGQ0Rh8, YouTube}, year = {2016}, date = {2016-01-01}, booktitle = {EuroVis 2016: Eurographics / IEEE VGTC Conference on Visualization 2016}, volume = {35}, number = {3}, pages = {351--360}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Monique Meuschke, Kai Lawonn, Benjamin Köhler, Uta Preim, Bernhard Preim Clustering of Aortic Vortex Flow in Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 182–187, 2016. BibTeX \| Links: @inproceedings{Meuschke_2016_BVM, title = {Clustering of Aortic Vortex Flow in Cardiac 4D PC-MRI Data}, author = {Monique Meuschke and Kai Lawonn and Benjamin Köhler and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/meuschke_2016_bvm.pdf, PDF Download}, year = {2016}, date = {2016-01-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {182--187}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2015
	Benjamin Köhler, Silvia Born, Roy van Pelt, Uta Preim, Bernhard Preim A Survey of Cardiac 4D PC-MRI Data Processing Inproceedings Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM), pp. 139–148, Chester, UK, 2015. BibTeX \| Links: @inproceedings{Koehler_2015_VCBM, title = {A Survey of Cardiac 4D PC-MRI Data Processing}, author = {Benjamin Köhler and Silvia Born and Roy van Pelt and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_vcbm.pdf, PDF Download}, year = {2015}, date = {2015-09-01}, booktitle = {Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM)}, pages = {139--148}, address = {Chester, UK}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Monique Meuschke, Uta Preim, Katharina Fischbach, Matthias Gutberlet, Bernhard Preim Two-Dimensional Plot Visualization of Aortic Vortex Flow in Cardiac 4D PC-MRI Data Inproceedings Proc. of Bildverarbeitung für die Medizin, pp. 257-261, 2015. BibTeX \| Links: @inproceedings{koehler_2015_bvm, title = {Two-Dimensional Plot Visualization of Aortic Vortex Flow in Cardiac 4D PC-MRI Data}, author = {Benjamin Köhler and Monique Meuschke and Uta Preim and Katharina Fischbach and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_bvm.pdf, PDF Download}, year = {2015}, date = {2015-01-01}, booktitle = {Proc. of Bildverarbeitung für die Medizin}, pages = {257-261}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Robust Cardiac Function Assessment in 4D PC-MRI Data of the Aorta and Pulmonary Artery Journal Article Comp Graph Forum, 2015. BibTeX \| Links: @article{Koehler_2015_CGF, title = {Robust Cardiac Function Assessment in 4D PC-MRI Data of the Aorta and Pulmonary Artery}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_cgf.pdf, PDF Download}, year = {2015}, date = {2015-01-01}, journal = {Comp Graph Forum}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Guided Analysis of Cardiac 4D PC-MRI Blood Flow Data Inproceedings Eurographics Short Papers and Medical Prize Awards, 2015. BibTeX \| Links: @inproceedings{Koehler_2015_EG, title = {Guided Analysis of Cardiac 4D PC-MRI Blood Flow Data}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_eg.pdf, PDF Download}, year = {2015}, date = {2015-01-01}, booktitle = {Eurographics Short Papers and Medical Prize Awards}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Motion-aware stroke volume quantification in 4D PC-MRI data of the human aorta Inproceedings International Journal of Computer-Assisted Radiology and Surgery (IJCARS), pp. 1–11, Springer, 2015. BibTeX \| Links: @inproceedings{Koehler_2015_IJCARS, title = {Motion-aware stroke volume quantification in 4D PC-MRI data of the human aorta}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_ijcars.pdf, PDF Download https://www.youtube.com/watch?v=sozt3TFwWPE, YouTube}, year = {2015}, date = {2015-01-01}, booktitle = {International Journal of Computer-Assisted Radiology and Surgery (IJCARS)}, pages = {1--11}, publisher = {Springer}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2014
	Benjamin Köhler, Uta Preim, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Robust Cardiac Function Assessment in 4D PC-MRI Data Inproceedings Proc. of Eurographics Workshop on Visual Computing for Biology and Medicine (EG VCBM), pp. 1–10, Wien, 2014. BibTeX \| Links: @inproceedings{Koehler_2014_VCBM, title = {Robust Cardiac Function Assessment in 4D PC-MRI Data}, author = {Benjamin Köhler and Uta Preim and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2014_vcbm.pdf, PDF Download}, year = {2014}, date = {2014-09-01}, booktitle = {Proc. of Eurographics Workshop on Visual Computing for Biology and Medicine (EG VCBM)}, pages = {1--10}, address = {Wien}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2013
	Benjamin Köhler, Rocco Gasteiger, Uta Preim, Holger Theisel, Matthias Gutberlet, Bernhard Preim Semi-Automatic Vortex Extraction in 4D PC-MRI Cardiac Blood Flow Data using Line Predicates Journal Article IEEE Transactions on Visualization and Computer Graphics (TVCG), 19(12) , pp. 2773–2782, 2013. BibTeX \| Links: @article{Koehler_2013_TVCG, title = {Semi-Automatic Vortex Extraction in 4D PC-MRI Cardiac Blood Flow Data using Line Predicates}, author = {Benjamin Köhler and Rocco Gasteiger and Uta Preim and Holger Theisel and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2013_tvcg.pdf, PDF Download https://www.youtube.com/watch?v=y3xf5WAFo2M, YouTube}, year = {2013}, date = {2013-01-01}, journal = {IEEE Transactions on Visualization and Computer Graphics (TVCG)}, volume = {19(12)}, pages = {2773--2782}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
2012
	Benjamin Köhler, Mathias Neugebauer, Rocco Gasteiger, Gábor Janiga, Oliver Speck, Bernhard Preim Surface-Based Seeding for Blood Flow Exploration Inproceedings Bildverarbeitung für die Medizin, pp. 81–86, Berlin, 2012. BibTeX \| Links: @inproceedings{Koehler_2012_BVM, title = {Surface-Based Seeding for Blood Flow Exploration}, author = {Benjamin Köhler and Mathias Neugebauer and Rocco Gasteiger and Gábor Janiga and Oliver Speck and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2012_bvm.pdf, PDF Download}, year = {2012}, date = {2012-00-01}, booktitle = {Bildverarbeitung für die Medizin}, pages = {81--86}, address = {Berlin}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close

2020
	Sebastian Ebel, Josefin Dufke, Benjamin Köhler, Bernhard Preim, Benjamin Behrendt, Boris Riekena, Bernd Jung, Christian Stehning, Siegfried Kropf, Matthias Grothoff, Matthias Gutberlet Automated quantitative extraction and analysis of 4D flow patterns in the ascending aorta -- an intraindividual comparison at 1.5 T and 3 T Journal Article Scientific reports, 10.2020 , pp. 9 Seiten, 2020. BibTeX @article{Ebel_2020, title = {Automated quantitative extraction and analysis of 4D flow patterns in the ascending aorta -- an intraindividual comparison at 1.5 T and 3 T}, author = {Sebastian Ebel and Josefin Dufke and Benjamin Köhler and Bernhard Preim and Benjamin Behrendt and Boris Riekena and Bernd Jung and Christian Stehning and Siegfried Kropf and Matthias Grothoff and Matthias Gutberlet}, year = {2020}, date = {2020-01-01}, journal = {Scientific reports}, volume = {10.2020}, pages = {9 Seiten}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
2019
	Sebastian Ebel, Josefin Dufke, Benjamin Köhler, Bernhard Preim, Susan Rosemeier, Bernd Jung, Michael Borger, Matthias Grothoff, Matthias Gutberlet Comparison of two accelerated 4D-Flow sequences for aortic flow quantification Inproceedings Scientific Reports, 2019. BibTeX @inproceedings{Ebel_2019_ScR, title = {Comparison of two accelerated 4D-Flow sequences for aortic flow quantification}, author = {Sebastian Ebel and Josefin Dufke and Benjamin Köhler and Bernhard Preim and Susan Rosemeier and Bernd Jung and Michael Borger and Matthias Grothoff and Matthias Gutberlet}, year = {2019}, date = {2019-01-01}, booktitle = {Scientific Reports}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Sebastian Ebel, Lisa Hübner, Benjamin Köhler, Siegfried Kropf, Bernhard Preim, Bernd Jung, Matthias Grothoff, Matthias Gutberlet Validation of two accelerated 4D flow MRI sequences at 3T: a phantom study Inproceedings European Radiology Experimental, pp. 1–12, Springer International Publishing, 2019. BibTeX \| Links: @inproceedings{Ebel_ERE_2019, title = {Validation of two accelerated 4D flow MRI sequences at 3T: a phantom study}, author = {Sebastian Ebel and Lisa Hübner and Benjamin Köhler and Siegfried Kropf and Bernhard Preim and Bernd Jung and Matthias Grothoff and Matthias Gutberlet}, url = {https://www.vismd.de/wp-content/uploads/legacy/ebel_ere_2019.pdf, PDF Download}, doi = {https://doi.org/10.1186/s41747-019-0089-2}, year = {2019}, date = {2019-01-01}, booktitle = {European Radiology Experimental}, volume = {3}, number = {1}, pages = {1--12}, publisher = {Springer International Publishing}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Bloodline: A system for the guided analysis of cardiac 4D PC-MRI data Journal Article Computers & Graphics, 82 , pp. 32–43, 2019. BibTeX \| Links: @article{Koehlerd, title = {Bloodline: A system for the guided analysis of cardiac 4D PC-MRI data}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.youtube.com/watch?v=Iyo-ge12qhI, YouTube}, doi = {10.1016/j.cag.2019.05.004}, year = {2019}, date = {2019-01-01}, journal = {Computers & Graphics}, volume = {82}, pages = {32--43}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
2018
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Visual and Quantitative Analysis of Great Arteries' Blood Flow Jets in Cardiac 4D PC-MRI Data Journal Article Computer Graphics Forum, 37 (3), pp. 195-204, 2018. BibTeX \| Links: @article{Koehler_2018_CGF, title = {Visual and Quantitative Analysis of Great Arteries' Blood Flow Jets in Cardiac 4D PC-MRI Data}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2018_cgf.pdf, PDF Download https://www.youtube.com/watch?v=WL7aw2XeAhY, YouTube}, doi = {10.1111/cgf.13412}, year = {2018}, date = {2018-01-01}, journal = {Computer Graphics Forum}, volume = {37}, number = {3}, pages = {195-204}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Pressure-based vortex extraction in cardiac 4D PC-MRI blood flow data Inproceedings EuroVis 2018: Eurographics / IEEE VGTC Conference on Visualization 2018, pp. to appear, 2018. BibTeX \| Links: @inproceedings{Koehler_2018_EuroVIS, title = {Pressure-based vortex extraction in cardiac 4D PC-MRI blood flow data}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2018_eurovis.pdf, PDF Download}, year = {2018}, date = {2018-01-01}, booktitle = {EuroVis 2018: Eurographics / IEEE VGTC Conference on Visualization 2018}, pages = {to appear}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Mickaël Francisco Sereno, Benjamin Köhler, Bernhard Preim Comparison of Divergence-Free Filters for Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 139–144, Springer Verlag, Erlangen, 2018. BibTeX \| Links: @inproceedings{Sereno_2018_BVM, title = {Comparison of Divergence-Free Filters for Cardiac 4D PC-MRI Data}, author = {Mickaël Francisco Sereno and Benjamin Köhler and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/sereno_2018_bvm.pdf, PDF Download}, year = {2018}, date = {2018-00-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {139--144}, publisher = {Springer Verlag}, address = {Erlangen}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2017
	Benjamin Köhler, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Visualization of Cardiac Blood Flow Using Anisotropic Ambient Occlusion for Lines Inproceedings Vision, Modelling und Visualization (VMV), Bonn, 2017. BibTeX \| Links: @inproceedings{Koehler_2017_VMV, title = {Visualization of Cardiac Blood Flow Using Anisotropic Ambient Occlusion for Lines}, author = {Benjamin Köhler and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2017_vmv.pdf, PDF Download https://www.youtube.com/watch?v=Y2_SFCFm6Hg, YouTube}, year = {2017}, date = {2017-00-01}, booktitle = {Vision, Modelling und Visualization (VMV)}, address = {Bonn}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2016
	Benjamin Behrendt, Benjamin Köhler, Daniel Gräfe, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Semi-Automatic Vessel Boundary Detection in Cardiac 4D PC-MRI Data Using FTLE fields Inproceedings Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM), pp. 41–46, Bergen, Norwegen, 2016. BibTeX \| Links: @inproceedings{Behrendt_2016_VCBM, title = {Semi-Automatic Vessel Boundary Detection in Cardiac 4D PC-MRI Data Using FTLE fields}, author = {Benjamin Behrendt and Benjamin Köhler and Daniel Gräfe and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/behrendt_2016_vcbm.pdf, PDF Download}, year = {2016}, date = {2016-09-01}, booktitle = {Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM)}, pages = {41--46}, address = {Bergen, Norwegen}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Behrendt, Benjamin Köhler, Uta Preim, Bernhard Preim Enhancing Visibility of Blood Flow in Volume Rendered Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 188–193, Berlin, 2016. BibTeX \| Links: @inproceedings{Behrendt_2016_BVM, title = {Enhancing Visibility of Blood Flow in Volume Rendered Cardiac 4D PC-MRI Data}, author = {Benjamin Behrendt and Benjamin Köhler and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/behrendt_2016_bvm.pdf, PDF Download https://www.youtube.com/watch?v=G0t9_2xSB28, YouTube}, year = {2016}, date = {2016-01-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {188--193}, address = {Berlin}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Silvia Born, Roy Van Pelt, Anja Hennemuth, Uta Preim, Bernhard Preim A Survey of Cardiac 4D PC-MRI Data Processing Journal Article Computer Graphics Forum, 2016. BibTeX \| Links: @article{Koehler_2016_CGF, title = {A Survey of Cardiac 4D PC-MRI Data Processing}, author = {Benjamin Köhler and Silvia Born and Roy Van Pelt and Anja Hennemuth and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2016_cgf.pdf, PDF Download}, year = {2016}, date = {2016-01-01}, journal = {Computer Graphics Forum}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Bernhard Preim Adaptive Animations of Vortex Flow Extracted from Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 194–199, 2016. BibTeX \| Links: @inproceedings{Koehler_2016_BVM, title = {Adaptive Animations of Vortex Flow Extracted from Cardiac 4D PC-MRI Data}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2016_bvm.pdf, PDF Download https://www.youtube.com/watch?v=6k9DTCvYXDs, YouTube}, year = {2016}, date = {2016-01-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {194--199}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Monique Meuschke, Benjamin Köhler, Uta Preim, Bernhard Preim, Kai Lawonn Semi-automatic Vortex Flow Classification in 4D PC-MRI Data of the Aorta Inproceedings EuroVis 2016: Eurographics / IEEE VGTC Conference on Visualization 2016, pp. 351–360, 2016. BibTeX \| Links: @inproceedings{Meuschke_2016_EuroVis, title = {Semi-automatic Vortex Flow Classification in 4D PC-MRI Data of the Aorta}, author = {Monique Meuschke and Benjamin Köhler and Uta Preim and Bernhard Preim and Kai Lawonn}, url = {https://www.vismd.de/wp-content/uploads/legacy/meuschke_2016_eurovis.pdf, PDF Download https://www.youtube.com/watch?v=steqJGQ0Rh8, YouTube}, year = {2016}, date = {2016-01-01}, booktitle = {EuroVis 2016: Eurographics / IEEE VGTC Conference on Visualization 2016}, volume = {35}, number = {3}, pages = {351--360}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Monique Meuschke, Kai Lawonn, Benjamin Köhler, Uta Preim, Bernhard Preim Clustering of Aortic Vortex Flow in Cardiac 4D PC-MRI Data Inproceedings Bildverarbeitung für die Medizin (BVM), pp. 182–187, 2016. BibTeX \| Links: @inproceedings{Meuschke_2016_BVM, title = {Clustering of Aortic Vortex Flow in Cardiac 4D PC-MRI Data}, author = {Monique Meuschke and Kai Lawonn and Benjamin Köhler and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/meuschke_2016_bvm.pdf, PDF Download}, year = {2016}, date = {2016-01-01}, booktitle = {Bildverarbeitung für die Medizin (BVM)}, pages = {182--187}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2015
	Benjamin Köhler, Silvia Born, Roy van Pelt, Uta Preim, Bernhard Preim A Survey of Cardiac 4D PC-MRI Data Processing Inproceedings Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM), pp. 139–148, Chester, UK, 2015. BibTeX \| Links: @inproceedings{Koehler_2015_VCBM, title = {A Survey of Cardiac 4D PC-MRI Data Processing}, author = {Benjamin Köhler and Silvia Born and Roy van Pelt and Uta Preim and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_vcbm.pdf, PDF Download}, year = {2015}, date = {2015-09-01}, booktitle = {Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM)}, pages = {139--148}, address = {Chester, UK}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Monique Meuschke, Uta Preim, Katharina Fischbach, Matthias Gutberlet, Bernhard Preim Two-Dimensional Plot Visualization of Aortic Vortex Flow in Cardiac 4D PC-MRI Data Inproceedings Proc. of Bildverarbeitung für die Medizin, pp. 257-261, 2015. BibTeX \| Links: @inproceedings{koehler_2015_bvm, title = {Two-Dimensional Plot Visualization of Aortic Vortex Flow in Cardiac 4D PC-MRI Data}, author = {Benjamin Köhler and Monique Meuschke and Uta Preim and Katharina Fischbach and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_bvm.pdf, PDF Download}, year = {2015}, date = {2015-01-01}, booktitle = {Proc. of Bildverarbeitung für die Medizin}, pages = {257-261}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Robust Cardiac Function Assessment in 4D PC-MRI Data of the Aorta and Pulmonary Artery Journal Article Comp Graph Forum, 2015. BibTeX \| Links: @article{Koehler_2015_CGF, title = {Robust Cardiac Function Assessment in 4D PC-MRI Data of the Aorta and Pulmonary Artery}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_cgf.pdf, PDF Download}, year = {2015}, date = {2015-01-01}, journal = {Comp Graph Forum}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Guided Analysis of Cardiac 4D PC-MRI Blood Flow Data Inproceedings Eurographics Short Papers and Medical Prize Awards, 2015. BibTeX \| Links: @inproceedings{Koehler_2015_EG, title = {Guided Analysis of Cardiac 4D PC-MRI Blood Flow Data}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_eg.pdf, PDF Download}, year = {2015}, date = {2015-01-01}, booktitle = {Eurographics Short Papers and Medical Prize Awards}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
	Benjamin Köhler, Uta Preim, Matthias Grothoff, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Motion-aware stroke volume quantification in 4D PC-MRI data of the human aorta Inproceedings International Journal of Computer-Assisted Radiology and Surgery (IJCARS), pp. 1–11, Springer, 2015. BibTeX \| Links: @inproceedings{Koehler_2015_IJCARS, title = {Motion-aware stroke volume quantification in 4D PC-MRI data of the human aorta}, author = {Benjamin Köhler and Uta Preim and Matthias Grothoff and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2015_ijcars.pdf, PDF Download https://www.youtube.com/watch?v=sozt3TFwWPE, YouTube}, year = {2015}, date = {2015-01-01}, booktitle = {International Journal of Computer-Assisted Radiology and Surgery (IJCARS)}, pages = {1--11}, publisher = {Springer}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2014
	Benjamin Köhler, Uta Preim, Matthias Gutberlet, Katharina Fischbach, Bernhard Preim Robust Cardiac Function Assessment in 4D PC-MRI Data Inproceedings Proc. of Eurographics Workshop on Visual Computing for Biology and Medicine (EG VCBM), pp. 1–10, Wien, 2014. BibTeX \| Links: @inproceedings{Koehler_2014_VCBM, title = {Robust Cardiac Function Assessment in 4D PC-MRI Data}, author = {Benjamin Köhler and Uta Preim and Matthias Gutberlet and Katharina Fischbach and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2014_vcbm.pdf, PDF Download}, year = {2014}, date = {2014-09-01}, booktitle = {Proc. of Eurographics Workshop on Visual Computing for Biology and Medicine (EG VCBM)}, pages = {1--10}, address = {Wien}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close
2013
	Benjamin Köhler, Rocco Gasteiger, Uta Preim, Holger Theisel, Matthias Gutberlet, Bernhard Preim Semi-Automatic Vortex Extraction in 4D PC-MRI Cardiac Blood Flow Data using Line Predicates Journal Article IEEE Transactions on Visualization and Computer Graphics (TVCG), 19(12) , pp. 2773–2782, 2013. BibTeX \| Links: @article{Koehler_2013_TVCG, title = {Semi-Automatic Vortex Extraction in 4D PC-MRI Cardiac Blood Flow Data using Line Predicates}, author = {Benjamin Köhler and Rocco Gasteiger and Uta Preim and Holger Theisel and Matthias Gutberlet and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2013_tvcg.pdf, PDF Download https://www.youtube.com/watch?v=y3xf5WAFo2M, YouTube}, year = {2013}, date = {2013-01-01}, journal = {IEEE Transactions on Visualization and Computer Graphics (TVCG)}, volume = {19(12)}, pages = {2773--2782}, keywords = {}, pubstate = {published}, tppubtype = {article} } Close
2012
	Benjamin Köhler, Mathias Neugebauer, Rocco Gasteiger, Gábor Janiga, Oliver Speck, Bernhard Preim Surface-Based Seeding for Blood Flow Exploration Inproceedings Bildverarbeitung für die Medizin, pp. 81–86, Berlin, 2012. BibTeX \| Links: @inproceedings{Koehler_2012_BVM, title = {Surface-Based Seeding for Blood Flow Exploration}, author = {Benjamin Köhler and Mathias Neugebauer and Rocco Gasteiger and Gábor Janiga and Oliver Speck and Bernhard Preim}, url = {https://www.vismd.de/wp-content/uploads/legacy/koehler_2012_bvm.pdf, PDF Download}, year = {2012}, date = {2012-00-01}, booktitle = {Bildverarbeitung für die Medizin}, pages = {81--86}, address = {Berlin}, keywords = {}, pubstate = {published}, tppubtype = {inproceedings} } Close

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